Thule unfortunately doesn't have a compatible base kit for a 2010 Lexus HS 250H to match with your aero crossbars and they unfortunately are not cross compatible with other brands so you would have to get a different roof rack for your vehicle. Rhino Rack is a great brand with honestly one of the best bang for your buck pricing models so I recommend going with one of their rack systems. For your Lexus you'll need the following components:
Rhino-Rack 2500 Series Legs for Vortex Aero Crossbars... view full answer...
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